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Reactions of the Fluorescent Sensor, Zinquin, with the Zinc-proteome: Adduct Formation and Ligand Substitution

Zinquin (ZQ) is a commonly used sensor for cellular Zn(2+) status. It has been assumed that measures accessible Zn(2+) concentrations in the nmolar range. Instead, this report shows a consistent pattern across seven mammalian cell and tissue types that ZQ reacts with micromolar concentrations of Zn(...

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Bibliografiske detaljer
Main Authors: Nowakowski, Andrew B., Petering, David H.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230276/
https://ncbi.nlm.nih.gov/pubmed/21905645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic201076w
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