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Enzymatic Processing of Platinated RNAs

The broadly prescribed anti-tumor drug cisplatin coordinates to DNA, altering the activity of cellular proteins whose functions rely upon sensing DNA structure. Cisplatin is also known to coordinate to RNA, but the effects of RNA-Pt adducts on the large number of proteins that process the transcript...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chapman, Erich G., DeRose, Victoria J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230263/
https://ncbi.nlm.nih.gov/pubmed/20099814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908419j
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