Molecular Basis for Activation of a Catalytic Asparagine Residue in a Self-Cleaving Bacterial Autotransporter

Autotransporters are secreted proteins produced by pathogenic Gram-negative bacteria. They consist of a membrane embedded β-domain and an extracellular passenger domain that is sometimes cleaved and released from the cell surface. We solved the structures of three non-cleavable mutants of the autotr...

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Detalhes bibliográficos
Main Authors: Barnard, Travis J., Gumbart, James, Peterson, Janine H., Noinaj, Nicholas, Easley, Nicole C., Dautin, Nathalie, Kuszak, Adam J., Tajkhorshid, Emad, Bernstein, Harris D., Buchanan, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230255/
https://ncbi.nlm.nih.gov/pubmed/22094314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.049
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