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Biophysical Assays to Probe the Mechanical Properties of the Interphase Cell Nucleus: Substrate Strain Application and Microneedle Manipulation

In most eukaryotic cells, the nucleus is the largest organelle and is typically 2 to 10 times stiffer than the surrounding cytoskeleton; consequently, the physical properties of the nucleus contribute significantly to the overall biomechanical behavior of cells under physiological and pathological c...

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Detalhes bibliográficos
Main Authors: Lombardi, Maria L., Zwerger, Monika, Lammerding, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230193/
https://ncbi.nlm.nih.gov/pubmed/21946671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3087
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