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Loss of Foxd3 Results in Decreased β-Cell Proliferation and Glucose Intolerance During Pregnancy

A complete molecular understanding of β-cell mass expansion will be useful for the improvement of therapies to treat diabetic patients. During normal periods of metabolic challenges, such as pregnancy, β-cells proliferate, or self-renew, to meet the new physiological demands. The transcription facto...

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Detalhes bibliográficos
Main Authors: Plank, Jennifer L., Frist, Audrey Y., LeGrone, Alison W., Magnuson, Mark A., Labosky, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230055/
https://ncbi.nlm.nih.gov/pubmed/21952247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1462
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