Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells.

The addition of bradykinin to NG108-15 cells results in a transient hyperpolarization followed by prolonged cell depolarization. Injection of inositol 1,4,5-trisphosphate or Ca2+ into the cytoplasm of NG108-15 cells also elicits cell hyperpolarization followed by depolarization. Tetraethylammonium i...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Higashida, H, Streaty, R A, Klee, W, Nirenberg, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3081891/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.942
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