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Preclinical stroke research – advantages and disadvantages of the most common rodent models of focal ischaemia
This review describes the most commonly used rodent models and outcome measures in preclinical stroke research and discusses their strengths and limitations. Most models involve permanent or transient middle cerebral artery occlusion with therapeutic agents tested for their ability to reduce stroke-...
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Formato: | Artigo |
Idioma: | Inglês |
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Blackwell Publishing Ltd
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229752/ https://ncbi.nlm.nih.gov/pubmed/21457227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01398.x |
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