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Theoretical calculation of relative binding affinity in host-guest systems.

The relative free energy of binding the anions Cl- and Br- to the macrotricyclic receptor SC24 in water has been computed by a computer simulation technique. This result and an incidental result for the relative free energy of hydration of the anions are in excellent agreement with experimental data...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lybrand, T P, McCammon, J A, Wipff, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC322963/
https://ncbi.nlm.nih.gov/pubmed/3456569
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