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Neighborhood Properties Are Important Determinants of Temperature Sensitive Mutations
Temperature-sensitive (TS) mutants are powerful tools to study gene function in vivo. These mutants exhibit wild-type activity at permissive temperatures and reduced activity at restrictive temperatures. Although random mutagenesis can be used to generate TS mutants, the procedure is laborious and u...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229608/ https://ncbi.nlm.nih.gov/pubmed/22164302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028507 |
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