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Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain.

An endogenous brain neuropeptide with 104 amino acid residues that modulates gamma-aminobutyric acid receptor function was termed DBI because it displaces diazepam from its specific brain binding sites. Tryptic digestion of DBI generates an octadecaneuropeptide (ODN) that is more potent than the par...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ferrero, P, Santi, M R, Conti-Tronconi, B, Costa, E, Guidotti, A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.827
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