Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV

Severe acute respiratory coronavirus (SARS-CoV) emerged in 2002, resulting in roughly 8000 cases worldwide and 10% mortality. The animal reservoirs for SARS-CoV precursors still exist and the likelihood of future outbreaks in the human population is high. The SARS-CoV papain-like protease (PLP) is a...

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Detalhes bibliográficos
Main Authors: Frieman, Matthew, Basu, Dipanwita, Matthews, Krystal, Taylor, Justin, Jones, Grant, Pickles, Raymond, Baric, Ralph, Engel, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229576/
https://ncbi.nlm.nih.gov/pubmed/22164298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028479
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