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Membrane-Type-3 Matrix Metalloproteinase (MT3-MMP) Functions as a Matrix Composition-Dependent Effector of Melanoma Cell Invasion

In primary human melanoma, the membrane-type matrix metalloproteinase, MT3-MMP, is overexpressed in the most aggressive nodular-type tumors. Unlike MT1-MMP and MT2-MMP, which promote cell invasion through basement membranes and collagen type I-rich tissues, the function of MT3-MMP in tumor progressi...

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Autors principals: Tatti, Olga, Arjama, Mariliina, Ranki, Annamari, Weiss, Stephen J., Keski-Oja, Jorma, Lehti, Kaisa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229567/
https://ncbi.nlm.nih.gov/pubmed/22164270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028325
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