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Caffeine Acts via A1 Adenosine Receptors to Disrupt Embryonic Cardiac Function
BACKGROUND: Evidence suggests that adenosine acts via cardiac A1 adenosine receptors (A1ARs) to protect embryos against hypoxia. During embryogenesis, A1ARs are the dominant regulator of heart rate, and A1AR activation reduces heart rate. Adenosine action is inhibited by caffeine, which is widely co...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229565/ https://ncbi.nlm.nih.gov/pubmed/22164264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028296 |
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