Neuroglobin-Deficiency Exacerbates Hif1A and c-FOS Response, but Does Not Affect Neuronal Survival during Severe Hypoxia In Vivo

BACKGROUND: Neuroglobin (Ngb), a neuron-specific globin that binds oxygen in vitro, has been proposed to play a key role in neuronal survival following hypoxic and ischemic insults in the brain. Here we address whether Ngb is required for neuronal survival following acute and prolonged hypoxia in mi...

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Autori principali: Hundahl, Christian Ansgar, Luuk, Hendrik, Ilmjärv, Sten, Falktoft, Birgitte, Raida, Zindy, Vikesaa, Jonas, Friis-Hansen, Lennart, Hay-Schmidt, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229544/
https://ncbi.nlm.nih.gov/pubmed/22164238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028160
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