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Improving the Alignment Quality of Consistency Based Aligners with an Evaluation Function Using Synonymous Protein Words

Most sequence alignment tools can successfully align protein sequences with higher levels of sequence identity. The accuracy of corresponding structure alignment, however, decreases rapidly when considering distantly related sequences (<20% identity). In this range of identity, alignments optimiz...

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Detalhes bibliográficos
Main Authors: Lin, Hsin-Nan, Notredame, Cédric, Chang, Jia-Ming, Sung, Ting-Yi, Hsu, Wen-Lian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229492/
https://ncbi.nlm.nih.gov/pubmed/22163274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027872
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