Modulation of Calcium-Dependent Inactivation of L-Type Ca(2+) Channels via β-Adrenergic Signaling in Thalamocortical Relay Neurons

Neuronal high-voltage-activated (HVA) Ca(2+) channels are rapidly inactivated by a mechanism that is termed Ca(2+)-dependent inactivation (CDI). In this study we have shown that β-adrenergic receptor (βAR) stimulation inhibits CDI in rat thalamocortical (TC) relay neurons. This effect can be blocked...

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Bibliographic Details
Main Authors: Rankovic, Vladan, Landgraf, Peter, Kanyshkova, Tatyana, Ehling, Petra, Meuth, Sven G., Kreutz, Michael R., Budde, Thomas, Munsch, Thomas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229489/
https://ncbi.nlm.nih.gov/pubmed/22164209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027474
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