Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints

BACKGROUND: The HIV-1 genome is subject to pressures that target the virus resulting in escape and adaptation. On the other hand, there is a requirement for sequence conservation because of functional and structural constraints. Mapping the sites of selective pressure and conservation on the viral g...

Full description

Saved in:
Bibliographic Details
Main Authors: Snoeck, Joke, Fellay, Jacques, Bartha, István, Douek, Daniel C, Telenti, Amalio
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229471/
https://ncbi.nlm.nih.gov/pubmed/22044801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-87
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items