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Effects of chronic intermittent ethanol exposure on orbitofrontal and medial prefrontal cortex-dependent behaviors in mice

In humans, stroke or trauma-induced damage to the orbitofrontal cortex (OFC) or medial prefrontal cortex (mPFC) results in impaired cognitive flexibility. Alcoholics also exhibit similar deficits in cognitive flexibility suggesting that the OFC and mPFC are susceptible to alcohol-induced dysfunction...

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Main Authors: Badanich, Kimberly A., Becker, Howard C., Woodward, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229192/
https://ncbi.nlm.nih.gov/pubmed/22122149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0025922
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