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Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis.

The RecA protein of Escherichia coli is required for SOS-induced mutagenesis in addition to its recombinational and regulatory roles. Most SOS-induced mutations probably occur during replication across a DNA lesion (targeted mutagenesis). We have suggested previously that RecA might participate in t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lu, C, Scheuermann, R H, Echols, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.619
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