Short synthetic oligodeoxyribonucleotide leader sequences enhance accumulation of human proinsulin synthesized in Escherichia coli.

Enhanced accumulation of human proinsulin synthesized in Escherichia coli has been achieved by inserting a short leader of homooligopeptide at the amino end of proinsulin. Out of 20 amino acid oligomers studied, (Ala)6, (Asn)6, (Cys)7, (Gln)7, (His)6, (Ser)6, and (Thr)6 leaders were the most effecti...

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Библиографические подробности
Главные авторы: Sung, W L, Yao, F L, Zahab, D M, Narang, S A
Формат: Artigo
Язык:Inglês
Опубликовано: 1986
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC322903/
https://ncbi.nlm.nih.gov/pubmed/3511472
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