PLCβ is Critical for T-cell Chemotaxis

Chemokines acting through G-protein-coupled receptors play an essential role in the immune response. Phosphatidylinositol-3-kinase and phospholipase-C are distinct signaling molecules that have been proposed in the regulation of chemokine-mediated cell migration. Studies with knockout mice have demo...

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Main Authors: Bach, Tami L., Chen, Qing-Min, Kerr, Wesley T., Choi, John K., Wu, Dianqing, Koretzky, Gary A., Zigmond, Sally, Abrams, Charles S.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228861/
https://ncbi.nlm.nih.gov/pubmed/17675482
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