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Are extended twin family designs worth the trouble? A comparison of the bias, precision, and accuracy of parameters estimated in four twin family models

The classical twin design (CTD) uses observed covariances from monozygotic and dizygotic twin pairs to infer the relative magnitudes of genetic and environmental causes of phenotypic variation. Despite its wide use, it is well known that the CTD can produce biased estimates if its stringent assumpti...

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Autori principali: Keller, Matthew C., Medland, Sarah E., Duncan, Laramie E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228846/
https://ncbi.nlm.nih.gov/pubmed/20013306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-009-9320-x
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