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Late Repression of NF-κB Activity by Invasive but Not Non-Invasive Meningococcal Isolates Is Required to Display Apoptosis of Epithelial Cells

Meningococcal invasive isolates of the ST-11 clonal complex are most frequently associated with disease and rarely found in carriers. Unlike carriage isolates, invasive isolates induce apoptosis in epithelial cells through the TNF-α signaling pathway. While invasive and non-invasive isolates are bot...

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Detalhes bibliográficos
Main Authors: Deghmane, Ala-Eddine, El Kafsi, Hela, Giorgini, Dario, Abaza, Aziza, Taha, Muhamed-Kheir
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228807/
https://ncbi.nlm.nih.gov/pubmed/22144896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002403
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