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Use of a reconstituted basement membrane to measure cell invasiveness and select for highly invasive tumor cells.

Malignant cells must traverse basement membranes during their migration to sites distant from the primary tumor. Since basement membranes are thought to be a critical barrier to the passage of tumor cells, we have constructed a model basement membrane-stromal matrix consisting of laminin and type IV...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Terranova, V P, Hujanen, E S, Loeb, D M, Martin, G R, Thornburg, L, Glushko, V
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.465
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