Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.

Recombinant human tumor necrosis factor (TNF), purified to greater than 99% homogeneity, increases surface expression of class I major histocompatibility complex (MHC) antigens to a maximum of 9-fold on cultured human endothelial cells (HEC) and human dermal fibroblasts (HDF). The increase is concen...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Collins, T, Lapierre, L A, Fiers, W, Strominger, J L, Pober, J S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322876/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.446
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