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Inhibition of heat shock protein synthesis by heat-inducible antisense RNA.

We show that antisense RNAs transcribed from genes that are stably integrated into the genome can be used to inhibit the expression of an endogenous cellular gene. Drosophila tissue culture cells were stably transformed with a gene encoding a heat-inducible RNA complementary to the message for hsp26...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: McGarry, T J, Lindquist, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.399
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