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The tumor promoter phorbol 12-myristate 13-acetate induces a program of altered gene expression similar to that induced by platelet-derived growth factor and transforming oncogenes.

Treatment of mouse NIH 3T3 cells with the phorbol ester tumor promoter, phorbol 12-myristate 13-acetate, results in altered transcription of several genes as measured in nuclear run-off experiments. The first set of genes, whose altered transcription occurs rapidly in the absence of protein synthesi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Principais autores: Rabin, M S, Doherty, P J, Gottesman, M M
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 1986
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.357
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