A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory

STAT3 transcription factor signaling in specific T helper cell differentiation have been well described, whereas the broader roles for STAT3 in lymphocyte memory are less clear. Patients with autosomal dominant hyper-IgE syndrome (AD-HIES) carry dominant negative STAT3 mutations and are susceptible...

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Detalhes bibliográficos
Main Authors: Siegel, Andrea M., Heimall, Jennifer, Freeman, Alexandra F., Hsu, Amy P., Brittain, Erica, Brenchley, Jason M., Douek, Daniel C., Fahle, Gary H., Cohen, Jeffrey I., Holland, Steven M., Milner, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228524/
https://ncbi.nlm.nih.gov/pubmed/22118528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.09.016
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