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The ADP Ribosylation Factor-Nucleotide Exchange Factors Gea1p and Gea2p Have Overlapping, but Not Redundant Functions in Retrograde Transport from the Golgi to the Endoplasmic Reticulum

The activation of the small ras-like GTPase Arf1p requires the action of guanine nucleotide exchange factors. Four Arf1p guanine nucleotide exchange factors have been identified in yeast: Sec7p, Syt1p, Gea1p, and its homologue Gea2p. We identified GEA2 as a multicopy suppressor of a sec21-3 temperat...

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Autors principals: Spang, Anne, Herrmann, Johannes M., Hamamoto, Susan, Schekman, Randy
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC32285/
https://ncbi.nlm.nih.gov/pubmed/11294905
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