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Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells

Neural crest stem cells can be isolated from differentiated cultures of human pluripotent stem cells, but the process is inefficient and requires cell sorting to obtain a highly enriched population. No specific method for directed differentiation of human pluripotent cells toward neural crest stem c...

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Bibliografiske detaljer
Main Authors: Menendez, Laura, Yatskievych, Tatiana A., Antin, Parker B., Dalton, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228464/
https://ncbi.nlm.nih.gov/pubmed/22084120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113746108
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