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In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid–polymeric nanoparticles

Following recent successes with percutaneous coronary intervention (PCI) for treating coronary artery disease (CAD), many challenges remain. In particular, mechanical injury from the procedure results in extensive endothelial denudation, exposing the underlying collagen IV-rich basal lamina, which p...

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Main Authors: Chan, Juliana M., Rhee, June-Wha, Drum, Chester L., Bronson, Roderick T., Golomb, Gershon, Langer, Robert, Farokhzad, Omid C.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228458/
https://ncbi.nlm.nih.gov/pubmed/22087004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115945108
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