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Construction of regulatory networks using expression time-series data of a genotyped population

The inference of regulatory and biochemical networks from large-scale genomics data is a basic problem in molecular biology. The goal is to generate testable hypotheses of gene-to-gene influences and subsequently to design bench experiments to confirm these network predictions. Coexpression of genes...

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Detalhes bibliográficos
Main Authors: Yeung, Ka Yee, Dombek, Kenneth M., Lo, Kenneth, Mittler, John E., Zhu, Jun, Schadt, Eric E., Bumgarner, Roger E., Raftery, Adrian E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228453/
https://ncbi.nlm.nih.gov/pubmed/22084118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116442108
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