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The therapeutic potential of inhibitors of the signal transducer and activator of transcription 3 for central nervous system malignancies

BACKGROUND: High-grade primary and metastatic central nervous system (CNS) tumors are common, deadly, and refractory to conventional therapy and continue to be therapeutically challenging. A key nodal transcriptional factor, the signal transducer and activator of transcription 3 (STAT3), drives the...

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Autor principal: Heimberger, Amy B.
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications Pvt Ltd 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228387/
https://ncbi.nlm.nih.gov/pubmed/22140648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2152-7806.89886
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