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Ankylosing spondylitis macrophages produce greater interleukin-23 in response to lipopolysaccharide without significant Unfolded Protein Response induction

OBJECTIVE: Previous work from the HLA-B27 transgenic rat model of ankylosing spondylitis (AS) suggests that macrophages develop an intracellular stress response called the Unfolded Protein Response (UPR) and as a result secrete increased cytokines in response to Toll like receptor agonists such as l...

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Detalhes bibliográficos
Main Authors: Zeng, Ling, Lindstrom, Mary J., Smith, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228355/
https://ncbi.nlm.nih.gov/pubmed/22127699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30593
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