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Altered enzymatic activity and allele frequency of OMI/HTRA2 in Alzheimer's disease

The serine-protease OMI/HTRA2, required for several cellular processes, including mitochondrial function, autophagy, chaperone activity, and apoptosis, has been implicated in the pathogenesis of both Alzheimer's disease (AD) and Parkinson's disease (PD). Western blot quantification of OMI/...

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Bibliographic Details
Main Authors: Westerlund, Marie, Behbahani, Homira, Gellhaar, Sandra, Forsell, Charlotte, Belin, Andrea Carmine, Anvret, Anna, Zettergren, Anna, Nissbrandt, Hans, Lind, Charlotta, Sydow, Olof, Graff, Caroline, Olson, Lars, Ankarcrona, Maria, Galter, Dagmar
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228343/
https://ncbi.nlm.nih.gov/pubmed/21163861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-163402
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