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Cytotoxic effects induced by docetaxel, gefitinib and cyclopamine on side population and non-side population cell fractions from human invasive prostate cancer cells

The present study has been undertaken to establish the therapeutic benefit of co-targeting epidermal growth factor receptor (EGFR) and sonic hedgehog pathways by using gefitinib and cyclopamine, respectively, for improving the efficacy of the current chemotherapeutic drug, docetaxel, to counteract t...

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Detalhes bibliográficos
Main Authors: Mimeault, Murielle, Johansson, Sonny L., Henichart, Jean-Pierre, Depreux, Patrick, Batra, Surinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228252/
https://ncbi.nlm.nih.gov/pubmed/20179163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-1013
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