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TOP2A Amplification in the Absence of That of HER-2/neu: Toward Individualization of Chemotherapeutic Practice in Breast Cancer

PRIMARY OBJECTIVE. To investigate the relationship between human epidermal growth factor receptor (HER)-2/neu and the gene encoding topoisomerase IIα (TOP2A) in breast cancer, while elucidating their association with clinicopathological variables. METHODS. Real-time quantitative polymerase chain rea...

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Detalhes bibliográficos
Main Authors: Glynn, Ronan W., Mahon, Sarah, Curran, Catherine, Callagy, Grace, Miller, Nicola, Kerin, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228145/
https://ncbi.nlm.nih.gov/pubmed/21705665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0071
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