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Characterization and distribution of receptors for the atrial natriuretic peptides in mammalian brain.

Both rat 125I-labeled atrial natriuretic polypeptide [125I-ANP or atrial natriuretic factor fragment ANF-(99-126)] and human 125I-ANP [125I-alpha-ANP or human ANF-(99-126)] bind with high specificity and affinity (Kd = 20-80 pM) to an apparent single class of sites in guinea pig brain. The ligand se...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Quirion, R, Dalpé, M, Dam, T V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.1.174
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