Functional channel formation associated with cytotoxic T-cell granules.

Lymphocyte granules from cytotoxic T-lymphocyte lines A2, A11, and R8 were enriched by subcellular fractionation using a Percoll gradient. Granule-enriched fractions showed potent hemolytic activity in the presence of Ca2+. Isolated granules induced rapid Ca2+-dependent membrane depolarization of J7...

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Detalhes bibliográficos
Main Authors: Young, J D, Nathan, C F, Podack, E R, Palladino, M A, Cohn, Z A
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC322809/
https://ncbi.nlm.nih.gov/pubmed/2417234
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