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The Evolving Role of Monoclonal Antibodies in Colorectal Cancer: Early Presumptions and Impact on Clinical Trial Development

Targeted biologic agents have an established role in treating metastatic colorectal cancer (mCRC). Bevacizumab, a recombinant monoclonal antibody against the vascular endothelial growth factor ligand is approved by the U.S. Food and Drug Administration (FDA) for bevacizumab-naïve patients. Cetuximab...

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Bibliographische Detailangaben
1. Verfasser: Eng, Cathy
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227885/
https://ncbi.nlm.nih.gov/pubmed/20067946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2009-0167
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