Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) central DNA Flap is generated during reverse transcription as a result of (+) strand initiation at the central polypurine tract (cPPT) and termination after a ca. 100 bp strand displacement at the central termination sequence (CTS). The cen...

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Main Authors: Iglesias, Candela, Ringeard, Mathieu, Di Nunzio, Francesca, Fernandez, Juliette, Gaudin, Raphael, Souque, Philippe, Charneau, Pierre, Arhel, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227589/
https://ncbi.nlm.nih.gov/pubmed/22074589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-92
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