Establishing Long-Term Efficacy in Chronic Disease: Use of Recursive Partitioning and Propensity Score Adjustment to Estimate Outcome in MS

CONTEXT: Establishing the long-term benefit of therapy in chronic diseases has been challenging. Long-term studies require non-randomized designs and, thus, are often confounded by biases. For example, although disease-modifying therapy in MS has a convincing benefit on several short-term outcome-me...

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Main Authors: Goodin, Douglas S., Jones, Jason, Li, David, Traboulsee, Anthony, Reder, Anthony T., Beckmann, Karola, Konieczny, Andreas, Knappertz, Volker
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227563/
https://ncbi.nlm.nih.gov/pubmed/22140424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022444
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