Ubiquitin Conjugation of Hepatitis B Virus Core Antigen DNA Vaccine Leads to Enhanced Cell-Mediated Immune Response in BALB/c Mice

BACKGROUND: Nearly 350 million persons worldwide are chronically infected with hepatitis B virus (HBV). Ubiquitin (Ub) is a highly conserved small regulatory protein, ubiquitous in eukaryotes, that usually serves as a signal for the target protein that is recognised and degraded in proteasomes . The...

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Bibliografiske detaljer
Main Authors: Chen, Jian-Hua, Yu, Yong-Sheng, Liu, Hong-Hong, Chen, Xiao-Hua, Xi, Min, Zang, Guo-Qing, Tang, Zheng-Hao
Format: Artigo
Sprog:Inglês
Udgivet: Kowsar 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227483/
https://ncbi.nlm.nih.gov/pubmed/22140385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/kowsar.1735143X.689
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