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Isochores and the Regulation of Gene Expression in the Human Genome

It is well established that changes in the phenotype depend much more on changes in gene expression than on changes in protein-coding genes, and that cis-regulatory sequences and chromatin structure are two major factors influencing gene expression. Here, we investigated these factors at the genome-...

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Bibliographic Details
Main Authors: Arhondakis, Stilianos, Auletta, Fabio, Bernardi, Giorgio
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227402/
https://ncbi.nlm.nih.gov/pubmed/21979159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr017
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