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Explaining the Structural Plasticity of α-Synuclein

[Image: see text] Given that α-synuclein has been implicated in the pathogenesis of several neurodegenerative disorders, deciphering the structure of this protein is of particular importance. While monomeric α-synuclein is disordered in solution, it can form aggregates rich in cross-β structure, rel...

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Autori principali: Ullman, Orly, Fisher, Charles K., Stultz, Collin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2011
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227348/
https://ncbi.nlm.nih.gov/pubmed/22029383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208657z
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