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Effects of glucagon on adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate in human plasma and urine

Glucagon, infused intravenously into fasting, well-hydrated, normal men in doses of 25-200 ng/kg per min, induced up to 30-fold increases in both plasma and urinary cyclic AMP. Cyclic GMP levels were unaffected by glucagon. Simultaneous cyclic AMP and inulin clearance studies demonstrated that the g...

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Bibliographic Details
Main Authors: Broadus, Arthur E., Kaminsky, Neil I., Northcutt, Robert C., Hardman, Joel G., Sutherland, Earl W., Liddle, Grant W.
Format: Artigo
Language:Inglês
Published: 1970
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC322724/
https://ncbi.nlm.nih.gov/pubmed/5480850
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