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Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
Single-molecule techniques for stretching DNA of contour lengths less than a kilobase are fraught with experimental difficulties. However, many interesting biological events such as histone binding and protein-mediated looping of DNA(1,2), occur on this length scale. In recent years, the mechanical...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3227192/ https://ncbi.nlm.nih.gov/pubmed/22025209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3405 |
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