The coenzyme A disulfide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host

In a microarray analysis of the RpoS regulon in mammalian host-adapted Borrelia burgdorferi, bb0728 (cdr) was found to be dually-transcribed by the sigma factors σ(70) and RpoS. The cdr gene encodes a coenzyme A disulfide reductase (CoADR) that reduces CoA-disulfides to CoA in an NADH-dependent mann...

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Detalhes bibliográficos
Main Authors: Eggers, Christian H., Caimano, Melissa J., Malizia, Robert A., Kariu, Toru, Cusack, Brian, Desrosiers, Daniel C., Hazlett, Karsten R.O., Claiborne, Al, Pal, Utpal, Radolf, Justin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226778/
https://ncbi.nlm.nih.gov/pubmed/21923763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07845.x
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