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Diverse Roles of Eph/ephrin Signaling in the Mouse Lens

Recent genetic studies show that the Eph/ephrin bidirectional signaling pathway is associated with both congenital and age-related cataracts in mice and humans. We have investigated the molecular mechanisms of cataractogenesis and the roles of ephrin-A5 and EphA2 in the lens. Ephrin-A5 knockout (-/-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Catherine, Gong, Xiaohua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226676/
https://ncbi.nlm.nih.gov/pubmed/22140528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028147
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