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A Knockout Mutation of a Constitutive GPCR in Tetrahymena Decreases Both G-Protein Activity and Chemoattraction

Although G-protein coupled receptors (GPCRs) are a common element in many chemosensory transduction pathways in eukaryotic cells, no GPCR or regulated G-protein activity has yet been shown in any ciliate. To study the possible role for a GPCR in the chemoresponses of the ciliate Tetrahymena, we have...

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Autori principali: Lampert, Thomas J., Coleman, Kevin D., Hennessey, Todd M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226668/
https://ncbi.nlm.nih.gov/pubmed/22140501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028022
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